Mega Spore Biotic

Once inside the large intestine, these dormant spores can change into their active, vegetative forms and begin colonizing in the gut. This unique probiotic blend aims toRECONDITIONthe gut instead of reseeding with probiotic strains that cannot survive digestion or colonize the gut. MegaSporeBiotic has quickly become a household favorite among health practitioners and consumers alike.

Revolutionary Probiotic and Microbiome Health Supplements

is a probiotic blend of 5 Bacillus spores that have been shown to maintain healthy gut barrier and immune function. The bi-phasic life cycle of the Bacillus spores allows them to remain dormant in harsh environments until they reach more favorable environments like the human gastrointestinal tract.

Why choose SPORE BASED?

Standard

Live Strain

Die off in heat or

stomach acid

Function by

'reseeding' their own strains

Spore Based

Probiotics

Survive stomach acid

& warm temperatures

Encourage thegrowth of

other other beneficial keystonebacteria

Bacillus Licheniformis

Produces proteases that aid protein digestion
Produces full spectrum of B vitamins

Bacillus Indicus HU36™

Produces carotenoids: lycopene, astaxanthin, beta-carotene, and lutein
Produces quinols and vitamins

Bacillus Subtilis HU58™

Produces nattokinase and vitamin K2
Supports healthy GALT development

Bacillus Clausii

Supports immune function

Bacillus Coagulans

Produces L+ optical form of lactic acid
Supports immune function

Ingredients and formula

With the launch of MegaSporeBiotic™, Microbiome Labs completely disrupted the probiotic industry, shifting the focus from reseeding to reconditioning the gut microbiome with the help of Bacillus spores.a

made without：

  • eggs

  • dairy

  • nuts

  • soy

  • wheat

  • gluten

    Backed by PublishedStudies

    In 60 days,MegaSporeBiotic™ Provided relief for occasional abdominal discomfort and supported elimination anddigestive health.


    No Refrigeration Required

    Week 1

    1 capsule every other day

    Week 2

    1 capsule daily

    Week 3+

    2 capsules daily

    How to use

    If 1 capsule every other day causes side effects, try starting with 1/2 capsules or even 1/4 capsule in some cases. Possible side effects may include abdominal cramping, loose stools, and changes in bowel movements. Though these side effects may be uncomfortable, they are a sign that the product is working! Side effects should resolve within 2-3 days.

    Science You Can Trust

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    Lives Changed

    Conferencesattended, exhibited,and/or

    Clinical Trialsinitiated and/orcompleted

    of Practitionerstrust us for key solutions

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    Research

    • McFarlin BK, Henning AL, Carbajal KM.

      Oral spore-based probiotic supplementation was associated with reduced incidence of post-prandial dietary endotoxin, triglycerides, and disease risk biomarkers. World J Gastrointest Pathophysiol. 2017 Aug 15; 8(3): 117–126.

    • Rhee KJ, Sethupathi P, Driks A, et al.

      Role of commensal bacteria in development of gut-associated lymphoid tissue and preimmune antibody repertoire. J Immunol. 2004;172(2):1118-24.

    • De Punder K, Pruimboom L.

      Stress induces endotoxemia and low-grade inflammation by increasing barrier permeability. Front Immunol. 2015;15(6):223.

    • Samanya M, Yamauchi K.

      Histological alterations of intestinal villi in chickens fed dried Bacillus subtilis var. natto. Comp Biochem Physiol A Mol Integr Physiol. 2002;133(1):95-104.

    • Gong Y, Li H, Li Y.

      Effects of Bacillus subtilis on epithelial tight junctions of mice with inflammatory bowel disease. J Interferon Cytokine Res. 2016;36(2).

    • Gibson GR, Rouzaud G, Brostoff J, et al.

      An evaluation of probiotic effects in the human gut: microbial aspects. Final Technical report. FSA project ref G01022.

    • Tam NKM, Uyen NQ, Hong HA, et al.

      The Intestinal Life Cycle of Bacillus subtilis and Close Relatives. Journal of Bacteriology. 2006;188(7):2692-2700.

    • Serra CR, Earl AM, Barbosa TM, et al.

      Sporulation during Growth in a Gut Isolate of Bacillus subtilis. J Bacteriol. 2014;196(23):4184-4196.

    • “Survival of Probiotics in Simulated Gastric Fluid.”

      Food Science Center Report. Silliker Labs. RPN 16663. August 24, 2013.

    • Lefevre M, Racedo SM, Ripert G, et al.

      Probiotic strain Bacillus subtilis CU1 stimulates immune system of elderly during common infectious disease period: a randomized, double-blind placebo-controlled study. Immun Aging. 2015;12:24.

    • Hong HA, Khaneja R, Tam NMK, et al.

      Bacillus subtilis isolated from the human gastrointestinal tract. Res Microbiol. 2009;160(2):134-143.

    • Mandel DR, Eichas K, Holmes J.

      Bacillus coagulans: a viable adjunct therapy for relieving symptoms of rheumatoid arthritis according to a randomized, controlled trial. BMC Complement Altern Med. 2010;10:1.

    • Marseglia GL, Tosca M, Cirillo I, et al.

      Efficacy of Bacillus clausii spores in the prevention of recurrent respiratory infections in children: a pilot study. Ther Clin Risk Manag. 2007;3(1):13-7.

    • Urdaci MC, Bressollier P, Pinchuk I, et al.

      Bacillus clausii probiotic strains: antimicrobial and immunomodulatory activities. J Clin Gastroenterol. 2004;38(6 Suppl):S86-90.

    • Nista EC, Candelli M, Cremonini F, et al.

      Bacillus clausii therapy to reduce side-effects of anti-Helicobacter pylori treatment: randomized, double-blind, placebo controlled trial. Aliment Pharmacol Ther. 2004 Nov;20(10):1181-8.

    • Gabrielli M, Lauritano EC, Scarpellini E, et al.

      Bacillus clausii as a Treatment of Small Intestinal Bacterial Overgrowth. Am J Gastroenterol. 2009;104(5):1327-8.

    • Di Caro S, Tao H, Grillo A, et al.

      Bacillus clausii effect on gene expression pattern in small bowel mucosa using DNA microarray analysis. Eur J Gastroenterol Hepatol. 2005;17(9):951-60.

    • Ciprandi G, Tosca MA, Milanese M, et al.

      Cytokines evaluation in nasal lavage of allergic children after Bacillus clausii administration: A pilot study. Pediatr Allergy Immunol. 2004;15(2):148-51.

    • Casula G, Cutting SM.

      Bacillus Probiotics: Spore Germination in the Gastrointestinal Tract. App Environ Microb. 2002;68(5):2344-2352.
        Others
      Survives high temperatures
      Reaches the intestines intact
      Encourages the growthof other beneficial flora